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How does upgrading to 0.096″ large‑bore access technology upgrade the value of a Comprehensive Stroke Center (Tier‑1)?

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For Comprehensive Stroke Centers aiming for Tier‑1 status, upgrading to 0.096″ large‑bore aspiration platforms that support Direct Aspiration First Pass (ADAPT) techniques can streamline recanalization, improve procedural efficiency, and align with volume‑based funding and ranking benchmarks. This shift helps centers standardize on high‑performance, evidence‑aligned technologies that may enhance first‑pass success, reduce procedure time, and position the center as a regional referral hub for acute ischemic stroke thrombectomy.

Penumbra BMX 9690CM large-bore access system

How does 0.096″ large‑bore access benefit ADAPT‑based stroke thrombectomy?

A 0.096″ internal‑diameter (ID) aspiration catheter provides a greater cross‑sectional lumen than standard 0.088″ systems, which can increase clot‑capture force and suction volume. This larger bore may allow more consistent first‑pass thrombectomy during ADAPT, reducing the need for adjunctive stent‑retriever use and shortening procedure time. For a Comprehensive Stroke Center, this translates into faster door‑to‑recanalization metrics that better position the institution in national rankings and value‑based‑care contracts.

In practice, 0.096″ platforms can be threaded through the same intermediate‑catheter or distal access systems used today, minimizing changes to existing workflows. When paired with a robust ADAPT‑focused protocol, the larger lumen can help maintain continuous aspiration, improve clot‑engagement stability, and reduce the likelihood of distal embolization. For Tier‑1 centers, adopting this spec as a “standard” can support a more uniform, high‑performance thrombectomy practice across operators.

Why are Tier‑1 stroke centers standardizing on ADAPT‑ready technology?

Tier‑1 Comprehensive Stroke Centers are under pressure to demonstrate not only high‑volume thrombectomy but also high‑quality outcomes and efficiency. Standardizing on ADAPT‑ready, large‑bore access devices signals a commitment to evidence‑aligned, first‑line aspiration‑based recanalization, which is increasingly reported in contemporary stroke‑thrombectomy literature. This standardization can reduce variability between operators, streamline device procurement, and strengthen the center’s case when applying for region‑specific medical‑funding packages tied to stroke‑care volume and outcomes.

From a business‑case perspective, a single proven ADAPT‑centric platform can lower the inventory footprint, simplify training, and accelerate protocol adoption. For centers already recognized as leaders, upgrading to 0.096″ systems can be framed as a “Tier‑1 upgrade” that reinforces their reputation and may attract higher‑complexity referrals. In a market where payers and regulators increasingly scrutinize stroke‑care metrics, consistent use of optimized access technology becomes a differentiator in contracting and benchmarking.

How does 0.096″ compare to 0.088″ systems in clot‑capture performance?

A 0.096″ ID catheter offers an approximately 18–20% greater circular cross‑sectional area than a 0.088″ system, which can enhance volumetric aspiration at the same negative pressure. This increased lumen can translate into higher clot‑capture force, reducing the chance that large or dense thrombi fragment or slip away during withdrawal. In ADAPT‑style thrombectomy, where the catheter is advanced directly across the clot and continuous aspiration is maintained, the larger bore may improve the likelihood of retrieving the entire clot in one pass.

From a physics perspective, the larger inner diameter also reduces flow resistance, allowing more effective suction transmission through curved or tortuous vascular segments. This can be especially important when navigating through the internal carotid or M1 segment, where coils and plaques introduce resistance. For a Tier‑1 center, moving from 0.088″ to 0.096″ is not merely a nominal spec change; it is a data‑driven upgrade that aligns with the trend toward using larger‑bore reperfusion catheters in acute ischemic stroke.

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Comparative spec snapshot (0.096″ vs 0.088″)

Parameter 0.096″ large‑bore aspiration catheter 0.088″ standard aspiration catheter
Internal diameter (ID) 0.096 in (≈2.44 mm) 0.088 in (≈2.24 mm)
Relative lumen area (approx.) ~18–20% larger Baseline reference
Clot‑capture force potential Higher, due to larger cross‑section Lower, smaller lumen
Typical ADAPT adaptation Designed or optimized for ADAPT Often originally for combo‑technique use

This table highlights how the 0.096″ platform can be positioned as a performance‑oriented upgrade from legacy 0.088″ systems, particularly when centers are preparing for Tier‑1 or higher‑tier stroke‑center audits.

What does a “Direct Aspiration First Pass” (ADAPT) protocol look like in a Tier‑1 center?

A Tier‑1 center’s ADAPT protocol typically treats large‑bore aspiration as the primary thrombectomy mechanism, reserving stent‑retriever use for rescue or difficult‑to‑access occlusions. The workflow begins with rapid imaging triage, followed by immediate groin access, placement of a large‑bore intermediate or distal access catheter, and tracking of the 0.096″ device directly to the clot under continuous aspiration. The operator advances the tip across the clot, then withdraws the catheter while maintaining vacuum, aiming to extract the thrombus in one or two passes.

Key protocol elements include standardized imaging windows, pre‑procedure team checklists, and clear criteria for when to escalate to stent retrievers or adjunctive techniques. Simulation‑based training and proctor‑led recertification help maintain uniform technique across interventionalists. For Tier‑1 centers, documenting ADAPT‑first, first‑pass, and TICI‑2b/3 rates becomes critical for benchmarking and pay‑for‑performance contracts.

How can 0.096″ technology support visualization and control during thrombectomy?

A larger‑bore catheter can improve visualization by allowing clearer contrast passage and more stable catheter‑tip positioning at the clot face. The 0.096″ ID can accommodate higher flow rates for flushing and contrast injection without over‑pressuring the local vasculature, which helps maintain a clean working field and reduces the need for repeated test‑injections. This combination can provide a more stable platform for real‑time angiographic monitoring during ADAPT, enabling operators to confirm clot engagement, track catheter movement, and recognize subtle signs of embolization or perforation earlier.

From a control standpoint, the slightly larger profile often comes with reinforced braiding or optimized shaft materials, which can enhance pushability and torque control as the catheter navigates tortuous anatomy. For a Tier‑1 center, this balance of visibility and control supports operator confidence, reduces the learning curve across less‑experienced neurointerventionalists, and contributes to more consistent procedural outcomes.

What are the commercial and operational impacts of upgrading to 0.096″ ADAPT platforms?

Upgrading to 0.096″ ADAPT‑ready systems can consolidate a stroke center’s thrombectomy inventory, potentially reducing the need for multiple competing catheter platforms. Tier‑1 centers often negotiate volume‑based contracts with suppliers, and standardizing on a single, high‑performance ADAPT‑centric product line can strengthen procurement leverage and simplify budgeting. Over time, fewer device types mean reduced training overhead, fewer inventory‑management errors, and faster onboarding for new operators.

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Operationally, a 0.096″ upgrade can be positioned as a “Tier‑1 enhancement” that aligns with regional ranking criteria and pay‑for‑performance incentives. As referral patterns shift toward centers that demonstrate consistent use of advanced recanalization techniques, the investment in 0.096″ technology can yield higher‑volume thrombectomy caseloads and stronger negotiation power with local health authorities and payers.

How can Tier‑1 centers build a case for bulk procurement of 0.096″ systems?

A compelling case for bulk procurement leans on three pillars: clinical evidence, efficiency metrics, and financial alignment. Stroke centers can reference contemporary ADAPT‑focused studies showing non‑inferior or superior first‑pass recanalization rates compared with stent‑retriever‑dominant approaches, then pair those with internal data on reduced procedure time, fewer devices per case, and lower complication rates. Demonstrating that 0.096″ technology can achieve these outcomes more consistently than 0.088″ systems strengthens the argument for centralizing on the larger‑bore platform.

From a conversion‑strategy perspective, decision‑makers should request side‑by‑side technical‑spec sheets and comparative‑performance summaries from vendors, then embed a “Request Bulk Quote / Technical Spec Sheet” call‑to‑action directly beneath the spec comparison. This allows hospital procurement teams to transition from capability‑driven decisions to cost‑per‑case modeling, which is essential for approval in volume‑based‑funding environments.

How does 0.096″ technology support regional leadership and CSC rankings?

Regional leadership in stroke care increasingly depends on the ability to perform high‑volume, high‑quality thrombectomy with reproducible protocols. Upgrading to 0.096″ large‑bore access systems that support ADAPT positions a Comprehensive Stroke Center as an early adopter of advanced recanalization technology, aligning with national and international stroke‑care guidelines that emphasize first‑pass success and procedural efficiency. Centers that standardize on this platform can highlight metrics such as TICI‑2b/3 recanalization rates, median procedure time, and reduced use of adjunctive devices when seeking higher‑tier status or regional designations.

In addition, public‑facing messaging about “Direct Aspiration First Pass” protocols backed by 0.096″ technology can differentiate the center from competitors that still rely on legacy 0.088″ systems. This differentiation can drive referral volume, attract stronger partnerships with academic institutions, and increase the center’s influence in regional stroke‑care networks.

ALLWILL Expert Views

“For Tier‑1 stroke centers, upgrading to 0.096″ ADAPT‑ready platforms is not just about catheter specs; it is about aligning clinical strategy with funding and ranking structures,” says an ALLWILL neurointerventional‑technology specialist. “ALLWILL’s data‑driven approach helps centers evaluate whether 0.096″ systems can meaningfully improve first‑pass success and reduce device‑related costs over time. By standardizing on a single, high‑performance platform, centers can strengthen their market position, simplify inventory, and build a more resilient, scalable stroke program that meets evolving regulatory and payer expectations.”

How can ALLWILL support a Tier‑1 stroke‑center upgrade?

ALLWILL supports Tier‑1 stroke centers by helping them select, validate, and implement 0.096″ ADAPT‑ready platforms that align with their clinical and commercial goals. The company’s Smart Center offers device inspection, repair, and refurbishment services, enabling centers to maintain high‑quality inventory while controlling capital and ongoing‑device costs. ALLWILL’s global infrastructure and technical‑support network can also assist with operator training, protocol development, and workflow‑optimization studies tailored to ADAPT‑centric stroke programs.

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In addition, ALLWILL’s data‑driven advisory services help centers model the impact of upgrading from 0.088″ to 0.096″ systems on procedure time, complication rates, and device‑cost per thrombectomy case. This analysis can become a critical input for business‑case submissions to hospital leadership and health‑authority boards, positioning the upgrade as a strategic investment rather than a routine device refresh.

How should Tier‑1 centers measure return on investment after upgrading to 0.096″ systems?

Tier‑1 centers should track a combination of clinical, operational, and financial metrics before and after the 0.096″ upgrade. Key indicators include median groin‑puncture‑to‑recanalization time, first‑pass TICI‑2b/3 rates, median number of devices used per thrombectomy, and rates of symptomatic intracranial hemorrhage and distal embolization. On the operational side, centers should monitor procedure‑room throughput, staff‑training time, and inventory‑turnover metrics.

Financial return‑on‑investment can be modeled by comparing the total‑device‑cost per thrombectomy, including aspiration catheters, stent retrievers, and adjunctive tools, against the volume of procedures and reimbursement linked to stroke‑care rankings. If the 0.096″ upgrade reduces reliance on secondary devices and shortens procedure time, the net savings and improved cash flow can outweigh the initial procurement cost. ALLWILL’s analytics‑enabled support can help centers translate these metrics into clear, board‑ready business‑case narratives that justify the upgrade.

Frequently Asked Questions

Why should a Tier‑1 stroke center upgrade from 0.088″ to 0.096″ systems?
A 0.096″ system offers a larger lumen than 0.088″ catheters, which can improve clot‑capture force, first‑pass success, and procedural speed in ADAPT‑based thrombectomy while supporting higher‑tier rankings and volume‑based funding models.

How does upgrading to 0.096″ affect training and workflow?
The upgrade typically requires minimal workflow change, as 0.096″ systems can be used with existing intermediate‑catheter setups; however, standardized ADAPT‑focused training helps ensure consistent technique and maximizes the performance benefits of the larger bore.

Can 0.096″ technology reduce the need for stent retrievers?
By improving first‑pass recanalization via more robust aspiration, 0.096″ systems may reduce the routine use of stent retrievers, lowering per‑case device costs and procedural complexity, though retrievers remain important for rescue scenarios.

How does ALLWILL support Tier‑1 stroke‑center device upgrades?
ALLWILL provides technical‑spec comparisons, device‑inspection and refurbishment services, and data‑driven modeling to help centers quantify the clinical and financial impact of moving from 0.088″ to 0.096″ ADAPT‑ready platforms.

Is 0.096″ large‑bore technology suitable for all large‑vessel occlusives?
Current evidence supports 0.096″ ADAPT‑ready catheters for most anterior‑circulation large‑vessel occlusions, but complex anatomy or highly calcified clots may still require rescue‑retriever strategies or adjunctive techniques tailored to individual‑patient characteristics.

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        12. PROPRIETARY RIGHTS.

(a) Ownership. No sale shall be construed as granting to Buyer any license or other right in, or to, any of MRP’s (i) patents; (ii) trademarks; (iii) internet domain names, whether or not trademarks, registered by any authorized private registrar or governmental authority, web addresses, web pages, websites and URLs; (iv) works of authorship, expressions, designs and design registrations, whether or not copyrightable, including copyrights and copyrightable works, software and firmware, technical data, data files, and databases and other specifications and documentation; (v) trade secrets; (vi) environmental or other testing applicable to the Equipment and/or the Services; and (vii) industrial and other intellectual property rights, and all rights, interests, and protections that are associated with, equivalent or similar to, or required for the exercise of, any of the foregoing, however arising, in each case whether registered or unregistered and including all registrations and applications for, and renewals or extensions of, such rights or forms of protection pursuant to the laws of any jurisdiction throughout in any part of the world (collectively, the “Intellectual Property Rights”).

(b) Prohibited Acts. Buyer shall not (i) take any action that might interfere with any of MRP’s rights in or to Intellectual Property Rights, including MRP’s ownership or exercise thereof; (ii) challenge any right, title, or interest of MRP in or to the Intellectual Property Rights; (iii) make any claim or take any action adverse to MRP’s ownership of the Intellectual Property Rights; (iv) register or apply for registrations, anywhere in the world, for MRP’s trademarks or any other trademark that is similar to MRP’s trademarks or that incorporates MRP’s trademarks in whole or in confusingly similar part; (v) use any mark, anywhere that is confusingly

similar to MRP’s trademarks in whole or in confusingly similar part; (vi) engage in any action that tends to disparage, dilute the value of or reflect negatively on the Equipment and/or the Services or any of MRP’s trademarks; (vii) misappropriate any of MRP’s trademarks for use as a domain name without prior written consent from MRP; or (viii) alter, obscure or remove any of MRP’s trademarks, or trademark or copyright notices or any other proprietary rights notices placed on the

Equipment, marketing materials or other materials that MRP may provide.

        13.  CONFIDENTIAL INFORMATION. Without the prior written consent of MRP,Buyer, directly or indirectly, shall not disclose (and will direct its directors, shareholders, employees and agents not to disclose) any Confidential Information. The term “Confidential Information” means any information of or relating to MRP or the Equipment and/or the Services not generally known to the public (other than as a result of disclosure in violation of this Agreement) in spoken, printed, electronic or any other form or medium, including, but not limited to, business processes, practices, methods, policies, plans, publications, documents, research, operations, services, strategies, techniques, agreements, contracts, transactions, potential transactions, know-how, trade secrets, databases, manuals, records, supplier information, financial information, accounting information, legal information, marketing information, pricing information, payroll information, personnel information, and supplier lists.

        14.  NON-SOLICITATION. Buyer agrees not to solicit or hire any personnel of MRP involved with the delivery of the Services during the provision of such Services and for twelve (12) months after the completion of such Services; provided, however, that Buyer may hire individuals employed by MRP who, without other solicitation, respond to advertisements or solicitations aimed at the general public.

        15.  EQUITABLE REMEDIES. Buyer acknowledges and agrees that (a) a breach or threatened breach by Buyer of any of its obligations under Sections 13 or 14 would give rise to irreparable harm to MRP for which monetary damages would not be an adequate remedy and (b) in the event of a breach or a threatened breach by Buyer of any such obligations, MRP shall, in addition to any and all other rights and remedies that may be available to MRP at law, at equity, or otherwise in respect of such breach, be entitled to equitable relief, including a temporary restraining order, an injunction, specific performance, and any other relief that may be available from a court of competent jurisdiction, without any requirement to post a bond or other security, and without any requirement to prove actual damages or that monetary damages will not afford an adequate remedy. Buyer agrees that Buyer will not oppose or otherwise challenge the appropriateness of equitable relief or the entry by a court of competent jurisdiction of an order granting equitable relief, in either case, consistent with the terms of this Section 15.

        16.  INDEMNIFICATION. Buyer agrees to indemnify, defend and hold harmless MRP and its directors, shareholders, employees and agents (collectively, “MRP Indemnitees”) against any liability, damage, loss or expense incurred by or imposed in connection with any claims, suits, actions, demands or judgments arising out of (a) any breach or non-fulfillment of any representation, warranty or covenant set forth in this Agreement by Buyer or its directors, managers, employees or agents (collectively, “Buyer’s Agents”); (b) any negligent act or omission or willful misconduct of Buyer or Buyer’s Agents in connection with this Agreement; (c) any bodily injury, death of any person or damage to real or tangible personal property caused by Buyer or Buyer’s Agents, including the use of unauthorized parts in or service of the Equipment; (d) any failure by Buyer or Buyer’s Agents to comply with any applicable laws; (e) any fraud or other intentional acts by Buyer or Buyer’s Agents; and (f) the use or operation of the Equipment, including, without limitation, any medical and/or surgical procedures performed by Buyer, and any of Buyer’s Agents, using the Equipment unless said damages are determined by a court of competence jurisdiction to be solely by the gross negligence of MRP or solely as result of a breach by MRP of the limited warranties contained herein.

        17.  DEFAULTS; REMEDIES. Notwithstanding anything herein to the contrary, should Buyer fail to pay for the order or any other amount, in whole or in part, when due or perform its other obligations under this Agreement or as otherwise mutually agreed in writing between Buyer and MRP (each, a “Default”), then MRP may take any and all actions available under law or equity to collect said amounts with a ten (10) day prior written notice, including, but not limited to, enforcing its security interest, accelerating the payment of and declaring immediately due and payable any unpaid balance of the order, referral to outside collection agencies and/or commencement of legal action. MRP’s rights shall be cumulative, and it shall not be required to have attempted to realize upon to the Equipment before taking any other collection actions. MRP may require that Buyer assemble and return any or all of the Equipment to MRP and, in the event Buyer fails to return such Equipment peaceably, enter upon the premises where such Equipment is located, with or without legal process, and repossess such Equipment. Upon a Default, Buyer agrees to pay upon MRP’s demand: (i) all costs and expenses incurred by MRP or its assignee in connection with the enforcement of any remedies, including all expenses incurred in connection with the return, sale, release or other disposition of the Equipment, including attorneys’ fees and other costs incurred by MRP or its assignee in enforcing or defending its rights and remedies under this Agreement and any other written agreement between Buyer and MRP.

        18.  COMPLIANCE WITH LAWS. Buyer shall (a) carry out the transactions contemplated by this sale and deal with the Equipment in conformity with all applicable laws, rules and regulations of all government authorities, including, without limitation, export laws, (b) obtain all permits and licenses required in connection with the purchase, shipment, installation or use of the Equipment, and (c) be solely responsible to fully understand and comply with laws, rules and regulations. Any information provided is as a convenience only.

        19.  FURTHER ASSURANCES. Upon MRP’s reasonable request, Buyer shall, at its sole cost and expense, execute and deliver all such further documents and instruments, and take all such further acts, necessary to give full effect to this Agreement.

        20.  ASSIGNMENT; SUCCESSORS AND ASSIGNS. Buyer cannot delegate any duties nor assign any rights or claims under this Agreement without MRP’s prior written consent, and any such attempt or assignment shall be void. In the event that Buyer finances its acquisition of any Equipment with a third party, Buyer may direct MRP to transfer title of such Equipment to such third-party financing company, with all remaining terms and conditions of this Agreement remaining in full force and effect. This Agreement is binding on and inures to the benefit of the parties to this Agreement and their respective permitted successors and permitted assigns.

        21.  NO THIRD-PARTY BENEFICIARIES. Subject to Section 16, this Agreement benefits solely the parties to this Agreement and their respective permitted successors and assigns, and nothing in this Agreement, express or implied, confers on any other person any legal or equitable right, benefit, or remedy of any nature whatsoever under or by reason of this Agreement.

        22.  GOVERNING LAW; VENUE. The application of the UN Convention on Contracts for the International Sale of Goods is expressly excluded. The parties agree that any and all claims, demands, disagreements, controversies or disputes arising out of or relating to this Agreement and any agreement or document delivered in connection herewith (collectively, “Claims”) shall be governed by and construed in accordance with the laws of the State of Utah and adjudicated exclusively in the state and federal courts located in or nearest to Summit County, Utah, which courts shall have the sole and exclusive jurisdiction and venue for adjudication of all Claims. The parties hereby agree upon, consent and stipulate to the jurisdiction and venue of the aforementioned courts for the adjudication of all Claims, to the exclusion of all other courts, forums and venues whatsoever.

        23.  NON-DISPARAGEMENT. Buyer shall not disparage MRP or MRP’s trademarks, websites, products or services, or display any such items in a derogatory or negative manner on any website or in any public forum or press release.

        24.  NOTICES. Any notice, demand, or communication required, permitted or desired to be given hereunder shall be deemed effectively given when personally delivered, when sent by electronic means, when received by overnight courier, or when mailed by prepaid, certified or registered mail, return receipt requested, addressed to the other party at its address set forth on the Quote or to such other address that the receiving party may designate from time to time in accordance with this Section 25.

        25.  PUBLIC ANNOUNCEMENTS. Unless otherwise stated herein, neither party shall issue a press release or otherwise advertise, make a public statement or disclose to any third-party information pertaining to the relationship arising under this Agreement, the existence or terms of this Agreement, the underlying transactions between MRP and Buyer or agent for Buyer or refer to the other party in relation to this Agreement without the other party’s prior written approval.

        26.  ENTIRE AGREEMENT; ADDITIONAL OR INCONSISTENT TERMS. Subject to Section 32, this Agreement constitutes the sole and entire agreement between the parties hereto relating to the subject matter hereof, and any unincorporated representation, affirmation of fact, course of prior dealings, promise or condition in connection therewith, or usage of the trade, shall not be binding on either party. Terms and conditions set forth which differ from, conflict with or are not included in this Agreement shall not be part of any agreement between MRP and Buyer unless both parties specifically accept such terms and conditions in writing.

        27.  WAIVER. No waiver under this Agreement is effective unless it is in writing and signed by the party waiving its right. Any waiver authorized on one occasion is effective only in that instance and only for the purpose stated and does not operate as a waiver on any future occasion. None of the following constitutes a waiver or estoppel of any right, remedy, power, privilege or condition arising from this Agreement: any failure or delay in exercising any right, remedy, power or privilege or in enforcing any condition under this Agreement; or any act, omission or course of dealing between the parties.

        28.  SURVIVAL. Subject to the limitations and other provisions of this Agreement, the representations and warranties of Buyer contained herein shall survive the expiration or earlier termination of this Agreement for a period of twelve (12) months after such expiration o termination and (b) this Section 29 and Sections 10, 12, 13, 14, 15, 16, 17, 21, 22, 23, 24, 26, and 32 of this Agreement, as well as any other provision that, in order to give proper effect to its intent, should survive such expiration or termination, shall survive the expiration or earlier termination of this Agreement. All other provisions of this Agreement shall not survive the expiration or earlier termination of this Agreement.

        29.  RELATIONSHIP OF PARTIES. Nothing in this Agreement creates any agency, joint venture, partnership or other form of joint enterprise, employment or fiduciary relationship between the parties. Neither party has any express or implied right or authority to assume or create any obligations on behalf of or in the name of the other party or to bind the other party to any contract, agreement or undertaking with any third party.

        30.  HEADINGS. The headings in this Agreement are for reference only and do not affect the interpretation of this Agreement.

        31.  ORDER OF PRECEDENCE. In the event of conflict between the Quote, a written agreement by MRP, and these Terms, the order of priority shall be: (1) the written

agreement by MRP, if only if executed by an MRP Officer, (2) the Quote and (3) these Terms, and only to the extent of the direct conflict. Notwithstanding the foregoing, MRP shall not be bound by, and specifically objects to, any terms, conditions or other provisions, both written and oral, which are different from, in addition to or inconsistent with the provisions of this Agreement which are set forth in any purchase order, receipt, acceptance, confirmation, correspondence or otherwise of, or by, Buyer. Fulfillment of Buyer’s order shall not constitute acceptance of any of Buyer’s terms and conditions and does not serve to modify or amend the terms and conditions contained herein.

        32.  SEVERABILITY. If any part of this Agreement is held to be void, illegal or unenforceable, then it shall be deemed to be severed from this Agreement and the remaining provisions shall continue in full force and effect; provided, however, that if any fundamental term or provision of this Agreement is held to be void, illegal or unenforceable, the remainder of this Agreement shall be unenforceable. Upon a determination that any term or provision is void, illegal or unenforceable, the parties shall negotiate in good faith to modify this Agreement to effect the original intent of the parties as closely as possible in order that the transactions contemplated hereby be consummated as originally contemplated to the greatest extent possible.