DISPOSABLES – GENERAL

High-Precision Single-Use Probes: Definition, Benefits, Technology, and Future Trends

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High-precision single-use probes are sterile, disposable medical and diagnostic tools engineered to capture highly accurate measurements or perform targeted interventions during a single procedure. They combine precise sensing or surgical performance with the safety and workflow advantages of a one-patient, one-probe design.

What Are High-Precision Single-Use Probes?

High-precision single-use probes are disposable instruments or sensors designed to measure, detect, or treat with a high degree of accuracy and repeatability, and then be safely discarded after one patient use. They are commonly used in patient monitoring, minimally invasive surgery, endoscopy, ophthalmology, interventional cardiology, critical care, and diagnostic imaging workflows. In this context, “high precision” refers to tight tolerances in measurement accuracy, stable calibration, responsive signal output, and consistent performance from device to device within a batch.

Typical examples include single-use Doppler flow probes for intraoperative blood flow verification, disposable cryo probes for retinal procedures, single-use biopsy and ablation probes, and disposable pressure or flow sensors integrated into catheter-based systems. High-precision single-use probes are delivered sterile, often in validated packaging, and are factory-calibrated to minimize onsite adjustment and to ensure that each device meets defined performance specifications. They are designed to interface seamlessly with consoles, monitoring systems, or energy sources so that clinicians can plug-and-play without waiting for sterilization or complex setup.

Clinical Use Cases for High-Precision Single-Use Probes

High-precision single-use probes span a wide range of clinical applications where accuracy and sterility are both critical. In surgery, intraoperative Doppler probes, cryo probes, and ablation probes provide targeted access to tissues and real-time hemodynamic feedback directly in the operative field. For vascular and cardiac procedures, disposable flow and pressure probes help confirm patency, assess gradients, and verify stent or graft effectiveness before closure. In endoscopy and interventional gastroenterology, single-use biopsy and sensing probes enhance tissue sampling, perfusion assessment, and lesion characterization while minimizing cross-contamination risks.

In critical care and anesthesia, single-use pressure transducers, temperature probes, and blood flow sensors are used for precise, continuous monitoring of vital parameters in high-acuity settings. In ophthalmology, single-use retinal cryo probes and diagnostics probes support delicate procedures where even minor contamination or performance variability can impact outcomes. High-precision single-use sensors are also increasingly used in fluid management systems, dialysis, extracorporeal circulation circuits, and infusion monitoring, where reliable readings of pressure, flow, or gas concentration are needed over defined time windows.

Market Trends and Growth Drivers for Single-Use Probes

Across the broader disposable device category, single-use instruments and probes are gaining share due to infection prevention, process efficiency, and regulatory pressure. The global biopsy devices market, which includes many single-use components, has been valued in the mid-single billions of dollars and is projected to nearly double over the next decade as demand for cancer diagnostics and image-guided procedures grows. Disposable biopsy forceps, as one proxy for single-use interventional tools, are expected to grow at a healthy pace as hospitals shift toward single-use endoscopic accessories driven by infection control regulations and the need to align with high-definition scopes.

More specific market analyses on disposable biopsy forceps forecast compound annual growth rates around the mid-single to high-single digits through the end of this decade, with gastrointestinal endoscopy accounting for a substantial portion of usage. Regions such as North America hold the largest market share due to advanced healthcare infrastructure and high procedural volumes, while Asia-Pacific is emerging as a fast-growing region thanks to increased healthcare spending and expanded endoscopic capabilities. At the same time, healthcare systems are weighing environmental concerns regarding medical waste and seeking more sustainable materials, recycling options, and packaging innovations in the single-use device segment.

Benefits of High-Precision Single-Use Probes for Infection Control

Infection prevention is one of the strongest adoption drivers for single-use probes and sensors. By design, single-use probes are used for one patient and then discarded, eliminating the risk of cross-contamination from incomplete reprocessing. Reusable instruments require meticulous cleaning, disinfection, and sterilization workflows that are prone to human error, complex validations, and high labor intensity. Disposable solutions, when packaged and handled correctly, provide a fresh sterile interface for every patient, which is especially critical in high-risk environments such as operating rooms, intensive care units, emergency departments, and endoscopy suites.

Healthcare-associated infections are a major cost and safety concern for health systems worldwide. Regulatory agencies and accreditation bodies continue to issue guidance and warnings around reprocessing failure, particularly for complex devices with lumens and difficult-to-clean surfaces. In this context, high-precision single-use probes offer a risk management advantage: they eliminate reprocessing variability and provide predictable sterility, lowering the likelihood of contamination-related adverse events. Clinical staff also benefit from simplified workflows when they no longer have to inspect, track, and document reprocessing cycles for complex reusable probes.

Operational Efficiency, Workflow, and Cost Considerations

Beyond infection prevention, high-precision single-use probes can significantly impact operational efficiency. Reprocessing reusable probes requires capital-intensive sterilization equipment, chemical consumables, trained staff, and adherence to detailed guidelines. By shifting to single-use probes, hospitals may reduce the time and expense associated with cleaning and sterilization, along with the downtime for instruments that are out of circulation during processing. This can shorten procedure turnover times and allow more consistent scheduling in high-volume areas such as endoscopy, interventional radiology, and surgery.

However, moving from reusable to single-use probes also introduces new cost considerations. Per-procedure supply costs increase, and materials management must carefully forecast, store, and distribute single-use probes to avoid shortages or overstock. The true cost comparison needs to account for sterilization infrastructure, reprocessing labor, repair and replacement of worn reusable probes, compliance risk, and infection-related costs. Many facilities find that high-precision single-use probes provide better cost predictability and reduce unplanned expenses tied to reprocessing failures or instrument damage. Others may adopt hybrid models where high-risk procedures rely on single-use probes while lower-risk areas continue using reusable instruments with robust reprocessing.

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Core Technology and Design of High-Precision Single-Use Probes

The technology behind high-precision single-use probes combines sensing elements, microelectronics, materials science, and manufacturing controls to achieve both performance and disposability. In medical sensors, single-use probes may incorporate piezoresistive, piezoelectric, optical, or capacitive elements to measure pressure, flow, temperature, or physiological signals with high fidelity. For intraoperative Doppler probes, ultrasonic transducers are engineered to emit and receive acoustic waves optimized for vascular assessment, enabling surgeons to confirm blood flow in real time.

High-precision single-use probes leverage advanced polymer molding, micro-machining, and embedded electronics to maintain narrow tolerances and repeatable outputs across large production volumes. Manufacturers often pre-calibrate these probes at the factory and encode calibration data into labels or, for more advanced systems, into onboard memory or connector interfaces. This allows seamless pairing with monitoring consoles or imaging systems, where the probe is recognized and configured automatically. The implementation of standardized connectors and protocols ensures that single-use probes integrate cleanly into clinical workflows without complex setup or user calibration.

Materials, Sterility, and Packaging Considerations

Materials selection for single-use probes must balance biocompatibility, mechanical robustness, manufacturability, and cost. Common choices include medical-grade polymers, stainless steel, and specialized coatings to minimize friction, improve tissue interaction, or enhance sensor accuracy. In fluid-contact applications, materials must withstand exposure to blood, saline, contrast media, or therapeutic agents without degrading or leaching harmful substances. For high-precision sensing, the stability of the sensor element and encapsulation materials under expected temperature and pressure ranges is critical.

Sterility assurance is fundamental for single-use probes. Devices are typically sterilized via ethylene oxide, gamma radiation, or other validated processes and then sealed in sterile barrier packaging that maintains sterility until point of use. Packaging design must protect delicate sensing elements and maintain calibration while still allowing easy opening in the procedural environment. Traceability elements such as lot numbers, manufacturing dates, and unique device identifiers support quality control and recall readiness. As sustainability becomes more important, manufacturers are exploring thinner yet robust barrier films, recyclable materials, and packaging designs that minimize waste without compromising sterility.

Types of High-Precision Single-Use Probes by Application

High-precision single-use probes can be categorized by their primary clinical domain. In surgical and interventional applications, disposable intraoperative Doppler probes help surgeons verify arterial and venous blood flow before closing an incision. Single-use cryo probes in ophthalmology support retinal tear treatment and retinopathy of prematurity interventions, providing predictable freezing performance without reprocessing delays. In cardiology and vascular surgery, single-use intravascular pressure or flow probes may be used during catheter-based and open procedures.

In endoscopy and minimally invasive diagnostics, single-use biopsy probes, forceps, and integrated sensor probes support accurate sampling and measurement under endoscopic visualization. In patient monitoring and critical care, high-precision single-use pressure transducers, temperature probes, and flow sensors attach to lines, catheters, or circuits and deliver accurate real-time data to monitors. Single-use sensors are also increasingly found in dialysis equipment, extracorporeal life support, infusion pumps, and closed-loop therapy systems, where their stable calibration and sterility simplify setup and reduce maintenance.

Market Data and Economic Opportunities

Market analyses consistently indicate that the demand for disposable biopsy devices and single-use endoscopic accessories is rising, driven by the dual forces of expanded procedural volumes and stricter infection prevention standards. Disposable biopsy forceps and related tools are projected to grow with compound annual rates that outpace some reusable device segments, as health systems look for ways to standardize performance and reduce reprocessing variability. The broader biopsy devices market is forecast to nearly double in value in roughly a decade, underscoring the importance of single-use biopsy and guidance probes in oncology care pathways.

Adjacent markets, such as single-use pressure and flow transducers, disposable endoscopy valves and buttons, and single-use surgical instruments, are also expanding as administrators adopt policies that favor disposable items in high-risk or high-throughput areas. While environmental concerns and waste management costs are prompting some facilities to reassess where single-use devices provide the greatest value, the overall trend in critical and interventional care is toward targeted use of high-precision single-use probes for procedures where infection risk and performance consistency are paramount. Manufacturers that can deliver cost-effective, high-performance disposable probes with clear clinical benefits are positioned to capture a growing share of this evolving market.

Top High-Precision Single-Use Probe Categories and Use Cases

Name Key Advantages Ratings Use Cases
Single-use intraoperative Doppler probes Real-time blood flow verification, immediate availability, optimized for surgical use High clinician satisfaction for vascular and transplant surgery Vascular surgery, neurosurgery, transplant procedures, bypass graft verification
Single-use retinal cryo probes Consistent freezing performance, sterile and ready to use, no purge cycles Strong adoption in retinal practices using cryotherapy Retinal tears, retinopathy of prematurity, scleral buckle procedures
Disposable biopsy and ablation probes Controlled sampling or energy delivery, designed for compatibility with endoscopic systems Widely accepted in GI and pulmonary endoscopy Gastrointestinal biopsy, pulmonary lesion sampling, local ablation procedures
Single-use pressure and flow sensors Factory-calibrated accuracy, plug-and-play with monitors, reduced cross-contamination High reliability in critical care and perfusion Hemodynamic monitoring, dialysis, ECMO, infusion monitoring
Single-use oximetry and physiological sensors Enhanced infection control, patient-specific sizing, simplified workflow Positive feedback in high-turnover units Pulse oximetry, neonatal monitoring, perioperative vital sign monitoring
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Competitor Comparison Matrix: Reusable vs Single-Use Probes

Feature High-Precision Single-Use Probes Reusable Probes
Infection control One-patient use, eliminate reprocessing-related cross-contamination risks Dependent on flawless cleaning and sterilization, subject to human error
Upfront cost Higher per-procedure device cost Higher capital cost for instruments and sterilization infrastructure
Lifecycle cost Predictable per-use costs, reduced maintenance and reprocessing labor Ongoing costs for reprocessing, potential repairs, and replacements
Performance consistency Factory-calibrated, consistent performance across units, no wear from repeated use Performance can degrade over time due to wear, damage, or repeated reprocessing
Workflow impact No sterilization delay, immediate availability, easier inventory planning for critical procedures Requires reprocessing turnaround time, potential bottlenecks if inventory is limited
Environmental impact Higher medical waste volume, potential recyclable packaging and materials under development Lower waste from instruments but high resource use for sterilization and chemicals

Real User Cases and ROI of High-Precision Single-Use Probes

Healthcare providers adopting high-precision single-use probes often report measurable clinical and operational benefits. A vascular surgery service that introduced single-use intraoperative Doppler probes, for example, might see a reduction in reoperation rates linked to unrecognized graft or anastomotic compromise, as surgeons are more likely to perform routine blood flow verification before closure. The ability to quickly connect a sterile, ready-to-use probe can reduce intraoperative delays associated with tracking down a clean reusable probe or waiting for processing, leading to smoother case flow.

In high-volume endoscopy units, moving from reusable to single-use biopsy tools and accessory probes can simplify scheduling by decoupling procedure volume from reprocessing capacity. Endoscopy nurses and techs spend less time managing sterilization logistics and more time on direct patient care and room turnover. These changes can add more procedures per day or reduce overtime costs. When infection-related complications are factored into cost analyses, facilities may find that the incremental per-procedure cost of high-precision single-use probes is offset by fewer hospital-acquired infections, shorter lengths of stay, and reduced readmissions.

ALLWILL is redefining B2B medical aesthetics by focusing on innovation, trust, and efficiency, offering brand-agnostic consultations and a Smart Center for inspection, repair, and refurbishment that helps practitioners optimize performance while reducing costs. Through its MET vendor management system and Lasermatch inventory platform, ALLWILL connects clients with vetted technicians, trainers, and device options, delivering transparent, data-driven solutions that streamline sourcing, maintenance, and technology upgrades.

Implementation Considerations: Quality, Calibration, and Regulatory Compliance

When implementing high-precision single-use probes, healthcare organizations need to evaluate product quality, calibration integrity, and compliance with relevant standards. Key considerations include accuracy specifications across the expected measurement range, stability over the intended duration of use, and compatibility with existing consoles or monitoring platforms. Facilities should confirm that single-use probes meet applicable regulatory requirements and standards for biocompatibility, electrical safety, and electromagnetic compatibility.

Calibration practices vary by manufacturer and application. Some high-precision single-use probes rely on fixed factory calibrations specified in accompanying documentation, while others may include encoded calibration factors that are automatically read by the host system. Clinicians and biomedical engineers should review how the probe’s performance is verified, how batch variations are controlled, and what quality assurance processes are in place to detect defects before distribution. Training staff on proper handling, storage, and use of single-use probes helps ensure that the realized clinical performance aligns with the intended high-precision design.

Environmental and Sustainability Challenges

The increased use of single-use probes poses environmental challenges related to medical waste generation. Disposable devices contribute to the volume of regulated medical waste that must be collected, treated, and disposed of according to strict guidelines. Waste management costs can be significant, and environmental sustainability initiatives are pushing healthcare organizations and manufacturers to reconsider packaging, materials, and supply chains. Some facilities are evaluating which procedures truly require single-use high-precision probes versus those where reusable options, supported by robust reprocessing, remain appropriate.

Manufacturers are responding by exploring more sustainable materials, reducing packaging volume, and collaborating with waste management partners to identify recycling or energy recovery options where feasible. Designers are increasingly considering lifecycle assessment data when developing new single-use probes, seeking ways to achieve high precision and sterility with lower environmental impact. Over time, regulatory pressure and stakeholder expectations may drive standardized reporting around the environmental footprint of single-use devices and encourage innovation in recyclable or bio-based materials.

Integration with Digital Health, AI, and Advanced Monitoring

As health systems adopt more digital and data-driven tools, high-precision single-use probes are becoming key enablers of advanced monitoring and decision support. Single-use pressure, flow, and physiological sensors can feed continuous streams of high-quality data into electronic health records, clinical decision support tools, predictive analytics platforms, and remote monitoring systems. The reliability and accuracy of these sensors are crucial when algorithms depend on the data to detect early deterioration, optimize fluid management, or automate alert thresholds.

In intraoperative and interventional settings, disposable probes that interface with digital imaging, navigation, and mapping systems enable more precise targeting and real-time feedback. As artificial intelligence expands into image-guided therapy and physiologic signal analysis, the consistency and calibration integrity of single-use probes become even more important to avoid bias or noise that could affect algorithm performance. Future generations of high-precision single-use probes may integrate identification chips, wireless communication, or onboard signal processing to improve traceability, simplify configuration, and support more sophisticated data analytics.

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Buying Guide: How to Evaluate High-Precision Single-Use Probes

Healthcare organizations evaluating high-precision single-use probes should start by aligning product selection with clinical requirements, procedural volumes, and infection control goals. Key evaluation criteria include measurement accuracy, response time, compatibility with existing consoles, ease of use, and ergonomics for the clinicians who will handle the probes. Product trials or pilot programs can help gather feedback from surgeons, anesthesiologists, nurses, and technicians regarding usability and perceived performance compared with existing solutions.

Cost analysis should extend beyond unit pricing to incorporate reprocessing savings, potential reductions in equipment downtime, and any expected impact on clinical outcomes such as infection rates or diagnostic yield. Supply chain and logistics teams must ensure that vendors can maintain reliable availability, handle surge demand, and support inventory management processes such as consignment or just-in-time delivery. Finally, collaboration with biomedical engineering and infection prevention teams is crucial to confirm that single-use high-precision probes meet institutional standards, integrate safely into existing systems, and align with broader quality and safety initiatives.

Future Trend Forecast for High-Precision Single-Use Probes

The future of high-precision single-use probes is shaped by converging trends in infection control, minimally invasive interventions, digital health, and sustainability. As more procedures move toward ambulatory and outpatient settings, the need for streamlined, low-maintenance, and reliable devices will favor disposable probes that eliminate reprocessing and support rapid turnover. Advances in sensor miniaturization, flexible electronics, and smart materials will enable new classes of single-use probes with enhanced performance and comfort, including wearable or implantable sensors designed for limited-duration monitoring.

In oncology, cardiology, and neurology, the integration of single-use probes with minimally invasive, image-guided techniques will expand. Single-use micro-sensors embedded in catheters, guidewires, or biopsy devices may provide richer physiological and structural data in real time. At the same time, environmental and regulatory pressures will drive manufacturers to rethink design and end-of-life management, encouraging more sustainable approaches without compromising sterility or precision. Facilities that strategically adopt high-precision single-use probes in areas with the greatest clinical and operational payoff will be best positioned to balance safety, efficiency, cost, and environmental responsibility.

FAQ

1) What are high-precision single-use probes?
High-precision single-use probes are disposable diagnostic or sampling tools engineered for ultra-accurate measurements in medical aesthetics. They reduce cross-contamination, ensure consistent results, and streamline waste management. By design, they support repeatable performance across procedures, enabling practitioners to operate with confidence and efficiency.

2) What are the key benefits for practitioners?
The main advantages include lower risk of contamination, improved measurement accuracy, reduced downtime for instrument recalibration, and simplified inventory management. They enable faster patient throughput while maintaining strict safety and quality standards, supporting better outcomes and productivity in clinics and aesthetic practices.

3) What is the core technology behind them?
These probes utilize advanced sensor materials, micro-fabrication techniques, and sterile packaging to preserve calibration. They integrate with device interfaces via secure connections and standardized protocols, ensuring reliable data capture and seamless workflow integration with existing equipment and software ecosystems.

4) What is the future trend outlook?
Expect broader adoption of single-use probes driven by stricter infection control, tighter regulatory scrutiny, and demand for precision data. Innovations may include smarter coatings, real-time quality feedback, and eco-friendly disposal options, all aimed at boosting accuracy and operational efficiency in high-throughput settings.

5) Who should consider using them?
Commercial stakeholders and decision-makers in medical aesthetics should evaluate these probes when prioritizing patient safety, data integrity, and device uptime. They are particularly beneficial for high-volume clinics, multi-site operators, and practices seeking to minimize cross-contamination risks.

6) How do they impact costs?
While unit costs are higher than reusable options, total cost of ownership can decline due to reduced maintenance, less downtime, and lower calibration risk. Inventory planning improves with predictable usage patterns, aiding budgeting and procurement efficiency.

7) What are the quality and compliance considerations?
Choose probes from suppliers with validated sterility, lot traceability, and clear sterilization statements. Ensure compatibility with your devices and confirm that the product adheres to relevant regulatory standards and quality management systems to avoid compliance issues.

8) What are the implementation best practices?
Establish a standardized procurement policy, train staff on proper handling and disposal, and align with device manufacturers’ recommended practices. Maintain an auditable usage log and integrate with your MET or inventory platform to optimize rollout and avoid stockouts.

Concise CTAs for Different Decision Stages

If you are in the early research stage, start by mapping where infection control risks, reprocessing bottlenecks, or precision gaps exist in your current workflows, then identify which procedures could benefit most from high-precision single-use probes. For organizations comparing vendors and device options, focus on evidence-backed performance, compatibility with your installed base, and the total cost of ownership that includes reprocessing, complications, and workflow impact. When you are ready to implement, design a structured rollout that includes pilot evaluations, staff training, and performance tracking so you can quantify gains in safety, efficiency, and clinical outcomes as you integrate high-precision single-use probes into everyday care.

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(c) Limited Warranties, If Any.

(i) If the Quote expressly states that the Equipment has a warranty for a certain time (a “Warranty Period”), then MRP warrants that the Equipment shall be in good working order under normal use for the Warranty Period, which Warranty Period shall commence from the date of delivery to Buyer (the “Delivery Date”), unless otherwise approved by an MRP Officer in writing, except for the following: (A) New (not used or pre-owned) Equipment that is to be serviced by MRP: if the Quote is silent, warranted to be in good working order under normal use for one hundred eighty (180) days from the Delivery Date; (B) Used Equipment sold refurbished by MRP: if the Quote is silent, warranted to be in good working order under normal use for thirty (30) days from the Delivery Date; (C) Consumable/disposable Equipment: if the Quote is silent, warranted to have been shipped from MRP in functional condition, and no additional warranty shall apply; no service shall be provided either. These items should be inspected for obvious damage, subject to Section 6 and 8(e), and MRP’s obligation under this warranty and this Section 8(c)(i)(C) is limited to replacement of the Equipment; and (D) New (not used or pre-owned) Equipment that is to be serviced by the manufacturer: if the Quote is silent, MRP makes no warranty for any such Equipment. Buyer’s sole warranty for any such Equipment, if any, shall be the original manufacturer’s warranty, which MRP agrees to pass on to Buyer, as applicable. (ii) For the limited warranties of Section 8(c)(i), including exceptions (A) and (B), but not (C) or this (D), Buyer is entitled to telephone, e-mail and video technical assistance and, subject to Sections 8(d) and 8(e), repair or replacement of such Equipment, in MRP’s sole discretion, should the Equipment become inoperative through normal use during the Warranty Period. Loaner equipment is not provided, but if so arranged by MRP, Buyer shall pay MRP the cash list price of any unreturned loaner equipment provided by MRP within seven (7) days of a written demand from MRP. (iii) Repair or replacement under any limited warranty of Equipment may be with parts or products that are new, used or refurbished, carrying the same limited warranty for the remaining term of the original item. Repairs or replacements shall not interrupt, extend or prolong the term of the warranty. (iv) For Services purchased under this Agreement, MRP warrants that the Services shall be performed using competent personnel in a professional manner in accordance with generally recognized industry standards for similar services. Subject to Sections 6 and 8(e) herein, if any Service was not performed in accordance with the aforementioned warranty, then MRP shall, in its sole discretion, either (A) repair or re-perform the applicable Service, or (B) credit or refund the price of such Service at the pro rata contract rate.

(d) Exclusions. MRP reserves the right, without liability, to void all warranties and remedies, including any obligation to service, repair, replace or otherwise remedy defects, errors or failures of the Equipment due to the occurrence of any of these events, and MRP shall be in no way responsible for: (i) handling, maintenance or use in a manner that is inconsistent with and/or contrary to the original manufacturer’s or MRP’s recommended procedures and/or instructions, including, without limitation, use of or with an unauthorized third-party good or part; (ii) any failure or damage resulting from negligence, alteration, modification or relocation of the Equipment by Buyer, its employees, agents or representatives; (iii) attempted or actual unauthorized dismantling, disassembling, service, repair, addition or change of the Equipment, including, without limitation, changing the serial number or shot count; (iv) abnormal wear and tear, including, without limitation, use under abnormal conditions (e.g., unclean, dusty, or exposure to extreme electromagnetic radiation, temperature or humidity); or (v) damage or failure of the Equipment due to a Force Majeure Event or a problem in the premises of the Equipment. In any of the above situations, or for any Equipment that has no warranty, MRP has sole discretion to service the Equipment, at Buyer’s expense, at MRP’s then-in-effect rates for service, labor, travel, shipping and materials.

(e) Notice and Inspection. The limited warranties contained in this Section 8 are made on condition that immediate written notice of any noncompliance with the Equipment’s and/or the Service’s warranty be given to MRP, and provided that MRP’s inspection reveals that Buyer’s claim is valid under the terms of such warranty.

        9.  DISCLAIMERS; NO OTHER WARRANTY. EXCEPT TO THE EXTENT AS PROVIDED IN SECTION 8(c)(i)(D), BUYER ACKNOWLEDGES THAT MRP IS NOT BOUND BY ANY WARRANTY THAT MAY BE SET FORTH IN A MANUFACTURER’S WRITTEN MATERIALS THAT WOULD HAVE APPLIED HAD BUYER PURCHASED THE EQUIPMENT DIRECTLY FROM THE MANUFACTURER IN ITS UNUSED STATE. BUYER ACKNOWLEDGES THAT BUYER HAS NOT RELIED UPON ANY WARRANTY OTHER THAN AS SET FORTH IN THIS AGREEMENT. IN ADDITION, BUYER ALSO HEREBY ACKNOWLEDGES AND AGREES THAT ANY ORAL OR WRITTEN STATEMENTS CONCERNING USE AND REGULATION OF MEDICAL DEVICES SOLD BY MRP ARE AND SHALL BE CONSTRUED AS FOR INFORMATIONAL PURPOSES ONLY AND WITHOUT WARRANTY OR ASSURANCE BY MRP AS TO THEIR ACCURACY OR VALIDITY. MRP ALSO HEREBY DISCLAIMS ANY AND ALL WARRANTIES REGARDING OTHER MEDICAL CARE OR HELP, INCLUDING THE SELECTION OF AESTHETIC AND MEDICAL PROCEDURES AND PRODUCTS FOR, OR CARE OF, PATIENTS. THE LIMITED WARRANTIES OF THIS AGREEMENT, IF APPLICABLE TO ANY EQUIPMENT OR SERVICE FURNISHED UNDER THIS AGREEMENT, CONSTITUTE THE ONLY WARRANTIES MADE WITH RESPECT TO THE EQUIPMENT AND/OR SERVICE AND ANY DEFECT, DEFICIENCY OR NONCONFORMITY. TO THE EXTENT PERMITTED BY LAW, SUCH WARRANTY IS IN LIEU OF ALL OTHER WARRANTIES, EXPRESS OR IMPLIED BY LAW, COURSE OF DEALING, COURSE OF PERFORMANCE, USAGE OF TRADE OR OTHERWISE, INCLUDING, BUT NOT LIMITED TO, ANY EXPRESS OR IMPLIED WARRANTY OF MERCHANTABILITY, TITLE, NONINFRINGEMENT OR FITNESS FOR A PARTICULAR PURPOSE.

        10.  LIMITATION OF LIABILITY. NOTWITHSTANDING ANYTHING TO THE CONTRARY IN THIS AGREEMENT, UNDER NO CIRCUMSTANCES SHALL MRP BE LIABLE FOR ANY INDIRECT, PUNITIVE, INCIDENTAL, CONSEQUENTIAL, EXEMPLARY OR SPECIAL DAMAGES, ARISING FROM, RELATED TO OR CAUSED, DIRECTLY OR INDIRECTLY, WHETHER FORESEEABLE OR NOT, BY THE EQUIPMENT AND/OR THE SERVICES, THE USE OR INABILITY TO USE THE EQUIPMENT, THE RESULTS GENERATED FROM THE EQUIPMENT AND/OR THE SERVICES, THIS AGREEMENT, ANY OTHER ACT OR OMISSION OF MRP, OR BASED UPON ANY OTHER LEGAL THEORY. IN NO EVENT SHALL MRP BE LIABLE FOR ANY LOSSES OF REVENUE, USE, BUSINESS OPPORTUNITY, PROFIT, SAVINGS OR ANY OTHER DAMAGES DUE TO ANY CAUSE WHATSOEVER, EVEN IF MRP OR ITS AGENTS HAS BEEN ADVISED OF THE POSSIBILITY THEREOF. THE FOREGOING IS A SEPARATE, ESSENTIAL TERM OF THIS AGREEMENT, AND SHALL BE EFFECTIVE UPON THE FAILURE OF ANY REMEDY, EXCLUSIVE OR NOT. IN NO EVENT WILL MRP’S TOTAL LIABILITY UNDER THIS AGREEMENT EXCEED THE PURCHASE PRICE ACTUALLY PAID TO MRP BY BUYER FOR THE EQUIPMENT AND/OR THE SERVICES GIVING RISE TO THE CLAIM FOR WHICH DAMAGES ARE BEING SOUGHT. NO SUIT OR ACTION MAY BE BROUGHT BY BUYER, ITS SHAREHOLDERS, DIRECTORS, MANAGERS, EMPLOYEES OR AGENTS FOR ANY BREACH OF THIS AGREEMENT MORE THAN ONE (1) YEAR AFTER THE ACCRUAL OF SUCH CAUSE OF ACTION. IT IS AGREED THAT MRP’S LIABILITY IS SO LIMITED. WITHOUT LIMITING THE GENERALITY OF THE FOREGOING, BUYER ASSUMES ALL RISK AND LIABILITY FOR THE RESULTS OBTAINED BY THE USE OF ANY EQUIPMENT IN THE PRACTICE OF ANY PROCESS, WHETHER IN TERMS OF OPERATING COSTS, GENERAL EFFECTIVENESS, SUCCESS OR FAILURE, AND REGARDLESS OF ANY ORAL OR WRITTEN STATEMENTS MADE BY MRP, BY WAY OF TECHNICAL ADVICE OR OTHERWISE, RELATED TO THE USE OF THE EQUIPMENT.

        11.  BUYER’S REPRESENTATIONS AND WARRANTIES. Buyer represents and warrants to MRP that: (a) Buyer is duly organized, validly existing, and in good standing in the jurisdiction of Buyer’s formation; (b) Buyer is duly qualified to do business and is in good standing in every jurisdiction in which such qualification is required; (c) Buyer has the full right, power, and authority to enter into this Agreement and to perform Buyer’s obligations under this Agreement; (d) the execution of this Agreement by the person whose signature is set forth at the end hereof has been duly authorized by all necessary corporate action of Buyer; (e) when executed and delivered by each of MRP and Buyer, this Agreement will constitute the legal, valid and binding obligation of Buyer, enforceable against Buyer in accordance with its terms; (f) Buyer is in compliance with all applicable laws relating to this Agreement, the Equipment and the operation of Buyer’s business; (g) Buyer is not insolvent and is paying all of its debts as they become due; and (h) all financial information that Buyer has provided to MRP is true and accurate and fairly represents Buyer’s financial condition.

        12. PROPRIETARY RIGHTS.

(a) Ownership. No sale shall be construed as granting to Buyer any license or other right in, or to, any of MRP’s (i) patents; (ii) trademarks; (iii) internet domain names, whether or not trademarks, registered by any authorized private registrar or governmental authority, web addresses, web pages, websites and URLs; (iv) works of authorship, expressions, designs and design registrations, whether or not copyrightable, including copyrights and copyrightable works, software and firmware, technical data, data files, and databases and other specifications and documentation; (v) trade secrets; (vi) environmental or other testing applicable to the Equipment and/or the Services; and (vii) industrial and other intellectual property rights, and all rights, interests, and protections that are associated with, equivalent or similar to, or required for the exercise of, any of the foregoing, however arising, in each case whether registered or unregistered and including all registrations and applications for, and renewals or extensions of, such rights or forms of protection pursuant to the laws of any jurisdiction throughout in any part of the world (collectively, the “Intellectual Property Rights”).

(b) Prohibited Acts. Buyer shall not (i) take any action that might interfere with any of MRP’s rights in or to Intellectual Property Rights, including MRP’s ownership or exercise thereof; (ii) challenge any right, title, or interest of MRP in or to the Intellectual Property Rights; (iii) make any claim or take any action adverse to MRP’s ownership of the Intellectual Property Rights; (iv) register or apply for registrations, anywhere in the world, for MRP’s trademarks or any other trademark that is similar to MRP’s trademarks or that incorporates MRP’s trademarks in whole or in confusingly similar part; (v) use any mark, anywhere that is confusingly

similar to MRP’s trademarks in whole or in confusingly similar part; (vi) engage in any action that tends to disparage, dilute the value of or reflect negatively on the Equipment and/or the Services or any of MRP’s trademarks; (vii) misappropriate any of MRP’s trademarks for use as a domain name without prior written consent from MRP; or (viii) alter, obscure or remove any of MRP’s trademarks, or trademark or copyright notices or any other proprietary rights notices placed on the

Equipment, marketing materials or other materials that MRP may provide.

        13.  CONFIDENTIAL INFORMATION. Without the prior written consent of MRP,Buyer, directly or indirectly, shall not disclose (and will direct its directors, shareholders, employees and agents not to disclose) any Confidential Information. The term “Confidential Information” means any information of or relating to MRP or the Equipment and/or the Services not generally known to the public (other than as a result of disclosure in violation of this Agreement) in spoken, printed, electronic or any other form or medium, including, but not limited to, business processes, practices, methods, policies, plans, publications, documents, research, operations, services, strategies, techniques, agreements, contracts, transactions, potential transactions, know-how, trade secrets, databases, manuals, records, supplier information, financial information, accounting information, legal information, marketing information, pricing information, payroll information, personnel information, and supplier lists.

        14.  NON-SOLICITATION. Buyer agrees not to solicit or hire any personnel of MRP involved with the delivery of the Services during the provision of such Services and for twelve (12) months after the completion of such Services; provided, however, that Buyer may hire individuals employed by MRP who, without other solicitation, respond to advertisements or solicitations aimed at the general public.

        15.  EQUITABLE REMEDIES. Buyer acknowledges and agrees that (a) a breach or threatened breach by Buyer of any of its obligations under Sections 13 or 14 would give rise to irreparable harm to MRP for which monetary damages would not be an adequate remedy and (b) in the event of a breach or a threatened breach by Buyer of any such obligations, MRP shall, in addition to any and all other rights and remedies that may be available to MRP at law, at equity, or otherwise in respect of such breach, be entitled to equitable relief, including a temporary restraining order, an injunction, specific performance, and any other relief that may be available from a court of competent jurisdiction, without any requirement to post a bond or other security, and without any requirement to prove actual damages or that monetary damages will not afford an adequate remedy. Buyer agrees that Buyer will not oppose or otherwise challenge the appropriateness of equitable relief or the entry by a court of competent jurisdiction of an order granting equitable relief, in either case, consistent with the terms of this Section 15.

        16.  INDEMNIFICATION. Buyer agrees to indemnify, defend and hold harmless MRP and its directors, shareholders, employees and agents (collectively, “MRP Indemnitees”) against any liability, damage, loss or expense incurred by or imposed in connection with any claims, suits, actions, demands or judgments arising out of (a) any breach or non-fulfillment of any representation, warranty or covenant set forth in this Agreement by Buyer or its directors, managers, employees or agents (collectively, “Buyer’s Agents”); (b) any negligent act or omission or willful misconduct of Buyer or Buyer’s Agents in connection with this Agreement; (c) any bodily injury, death of any person or damage to real or tangible personal property caused by Buyer or Buyer’s Agents, including the use of unauthorized parts in or service of the Equipment; (d) any failure by Buyer or Buyer’s Agents to comply with any applicable laws; (e) any fraud or other intentional acts by Buyer or Buyer’s Agents; and (f) the use or operation of the Equipment, including, without limitation, any medical and/or surgical procedures performed by Buyer, and any of Buyer’s Agents, using the Equipment unless said damages are determined by a court of competence jurisdiction to be solely by the gross negligence of MRP or solely as result of a breach by MRP of the limited warranties contained herein.

        17.  DEFAULTS; REMEDIES. Notwithstanding anything herein to the contrary, should Buyer fail to pay for the order or any other amount, in whole or in part, when due or perform its other obligations under this Agreement or as otherwise mutually agreed in writing between Buyer and MRP (each, a “Default”), then MRP may take any and all actions available under law or equity to collect said amounts with a ten (10) day prior written notice, including, but not limited to, enforcing its security interest, accelerating the payment of and declaring immediately due and payable any unpaid balance of the order, referral to outside collection agencies and/or commencement of legal action. MRP’s rights shall be cumulative, and it shall not be required to have attempted to realize upon to the Equipment before taking any other collection actions. MRP may require that Buyer assemble and return any or all of the Equipment to MRP and, in the event Buyer fails to return such Equipment peaceably, enter upon the premises where such Equipment is located, with or without legal process, and repossess such Equipment. Upon a Default, Buyer agrees to pay upon MRP’s demand: (i) all costs and expenses incurred by MRP or its assignee in connection with the enforcement of any remedies, including all expenses incurred in connection with the return, sale, release or other disposition of the Equipment, including attorneys’ fees and other costs incurred by MRP or its assignee in enforcing or defending its rights and remedies under this Agreement and any other written agreement between Buyer and MRP.

        18.  COMPLIANCE WITH LAWS. Buyer shall (a) carry out the transactions contemplated by this sale and deal with the Equipment in conformity with all applicable laws, rules and regulations of all government authorities, including, without limitation, export laws, (b) obtain all permits and licenses required in connection with the purchase, shipment, installation or use of the Equipment, and (c) be solely responsible to fully understand and comply with laws, rules and regulations. Any information provided is as a convenience only.

        19.  FURTHER ASSURANCES. Upon MRP’s reasonable request, Buyer shall, at its sole cost and expense, execute and deliver all such further documents and instruments, and take all such further acts, necessary to give full effect to this Agreement.

        20.  ASSIGNMENT; SUCCESSORS AND ASSIGNS. Buyer cannot delegate any duties nor assign any rights or claims under this Agreement without MRP’s prior written consent, and any such attempt or assignment shall be void. In the event that Buyer finances its acquisition of any Equipment with a third party, Buyer may direct MRP to transfer title of such Equipment to such third-party financing company, with all remaining terms and conditions of this Agreement remaining in full force and effect. This Agreement is binding on and inures to the benefit of the parties to this Agreement and their respective permitted successors and permitted assigns.

        21.  NO THIRD-PARTY BENEFICIARIES. Subject to Section 16, this Agreement benefits solely the parties to this Agreement and their respective permitted successors and assigns, and nothing in this Agreement, express or implied, confers on any other person any legal or equitable right, benefit, or remedy of any nature whatsoever under or by reason of this Agreement.

        22.  GOVERNING LAW; VENUE. The application of the UN Convention on Contracts for the International Sale of Goods is expressly excluded. The parties agree that any and all claims, demands, disagreements, controversies or disputes arising out of or relating to this Agreement and any agreement or document delivered in connection herewith (collectively, “Claims”) shall be governed by and construed in accordance with the laws of the State of Utah and adjudicated exclusively in the state and federal courts located in or nearest to Summit County, Utah, which courts shall have the sole and exclusive jurisdiction and venue for adjudication of all Claims. The parties hereby agree upon, consent and stipulate to the jurisdiction and venue of the aforementioned courts for the adjudication of all Claims, to the exclusion of all other courts, forums and venues whatsoever.

        23.  NON-DISPARAGEMENT. Buyer shall not disparage MRP or MRP’s trademarks, websites, products or services, or display any such items in a derogatory or negative manner on any website or in any public forum or press release.

        24.  NOTICES. Any notice, demand, or communication required, permitted or desired to be given hereunder shall be deemed effectively given when personally delivered, when sent by electronic means, when received by overnight courier, or when mailed by prepaid, certified or registered mail, return receipt requested, addressed to the other party at its address set forth on the Quote or to such other address that the receiving party may designate from time to time in accordance with this Section 25.

        25.  PUBLIC ANNOUNCEMENTS. Unless otherwise stated herein, neither party shall issue a press release or otherwise advertise, make a public statement or disclose to any third-party information pertaining to the relationship arising under this Agreement, the existence or terms of this Agreement, the underlying transactions between MRP and Buyer or agent for Buyer or refer to the other party in relation to this Agreement without the other party’s prior written approval.

        26.  ENTIRE AGREEMENT; ADDITIONAL OR INCONSISTENT TERMS. Subject to Section 32, this Agreement constitutes the sole and entire agreement between the parties hereto relating to the subject matter hereof, and any unincorporated representation, affirmation of fact, course of prior dealings, promise or condition in connection therewith, or usage of the trade, shall not be binding on either party. Terms and conditions set forth which differ from, conflict with or are not included in this Agreement shall not be part of any agreement between MRP and Buyer unless both parties specifically accept such terms and conditions in writing.

        27.  WAIVER. No waiver under this Agreement is effective unless it is in writing and signed by the party waiving its right. Any waiver authorized on one occasion is effective only in that instance and only for the purpose stated and does not operate as a waiver on any future occasion. None of the following constitutes a waiver or estoppel of any right, remedy, power, privilege or condition arising from this Agreement: any failure or delay in exercising any right, remedy, power or privilege or in enforcing any condition under this Agreement; or any act, omission or course of dealing between the parties.

        28.  SURVIVAL. Subject to the limitations and other provisions of this Agreement, the representations and warranties of Buyer contained herein shall survive the expiration or earlier termination of this Agreement for a period of twelve (12) months after such expiration o termination and (b) this Section 29 and Sections 10, 12, 13, 14, 15, 16, 17, 21, 22, 23, 24, 26, and 32 of this Agreement, as well as any other provision that, in order to give proper effect to its intent, should survive such expiration or termination, shall survive the expiration or earlier termination of this Agreement. All other provisions of this Agreement shall not survive the expiration or earlier termination of this Agreement.

        29.  RELATIONSHIP OF PARTIES. Nothing in this Agreement creates any agency, joint venture, partnership or other form of joint enterprise, employment or fiduciary relationship between the parties. Neither party has any express or implied right or authority to assume or create any obligations on behalf of or in the name of the other party or to bind the other party to any contract, agreement or undertaking with any third party.

        30.  HEADINGS. The headings in this Agreement are for reference only and do not affect the interpretation of this Agreement.

        31.  ORDER OF PRECEDENCE. In the event of conflict between the Quote, a written agreement by MRP, and these Terms, the order of priority shall be: (1) the written

agreement by MRP, if only if executed by an MRP Officer, (2) the Quote and (3) these Terms, and only to the extent of the direct conflict. Notwithstanding the foregoing, MRP shall not be bound by, and specifically objects to, any terms, conditions or other provisions, both written and oral, which are different from, in addition to or inconsistent with the provisions of this Agreement which are set forth in any purchase order, receipt, acceptance, confirmation, correspondence or otherwise of, or by, Buyer. Fulfillment of Buyer’s order shall not constitute acceptance of any of Buyer’s terms and conditions and does not serve to modify or amend the terms and conditions contained herein.

        32.  SEVERABILITY. If any part of this Agreement is held to be void, illegal or unenforceable, then it shall be deemed to be severed from this Agreement and the remaining provisions shall continue in full force and effect; provided, however, that if any fundamental term or provision of this Agreement is held to be void, illegal or unenforceable, the remainder of this Agreement shall be unenforceable. Upon a determination that any term or provision is void, illegal or unenforceable, the parties shall negotiate in good faith to modify this Agreement to effect the original intent of the parties as closely as possible in order that the transactions contemplated hereby be consummated as originally contemplated to the greatest extent possible.