L&C BIO FILL® MegaFill, Code 131100, Size 350mg

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Part #: Code 131100, Size 350mg

$140.00

SKU: Code 131100, Size 350mg Category:
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Description

From an institutional asset management and clinical procurement standpoint, soft tissue reconstruction materials must mitigate the risk of host rejection while maximizing surgical predictability. Utilizing low-quality or sub-standard dermal matrices often leads to severe postoperative inflammatory responses, graft resorption, and secondary revision surgeries, which drastically inflate institutional liabilities and compromise clinical compliance.

The L&C BIO FILL® MegaFill (350mg) provides procurement managers and biomedical engineers with an authorized, highly stable biological graft. By eliminating the need for autologous tissue harvesting, it shortens overall operating room (OR) times, mitigates donor-site morbidity, and optimizes clinical resource allocation.


Advanced Technical Architecture & Clinical Benefits

  • AlloClean® Purification Technology: This proprietary process thoroughly extracts all epidermal structures, cellular components, and potential pathogenetic antigens. By removing these immunogenic triggers, it drastically minimizes the risk of graft versus host disease (GVHD), severe tissue necrosis, and chronic foreign body reactions.

  • Intact 3D Extracellular Matrix (ECM) Scaffold: The purification sequence preserves the natural three-dimensional architecture composed of native collagen and elastin fibers. This intact structural blueprint accelerates host fibroblast infiltration and rapid neovascularization (angiogenesis), facilitating predictable tissue remodeling rather than fibrous encapsulation.

  • Advanced Cross-Linking Processing: Balanced cross-linking optimizes the equilibrium between structural persistence and biological activity. This prevents premature enzymatic degradation and volume loss, ensuring long-term structural volume stability in complex contour reconstructions.

  • Electron Beam (E-Beam) Irradiation Sterilization: Delivered as a sterile, lyophilized (freeze-dried) single-use unit, E-beam sterilization ensures a high Sterility Assurance Level (SAL) without altering the mechanical integrity of the collagen matrix. This mitigates bacterial contamination risks and maintains clinical compliance.

  • Ambient Temperature Storage Stability: Engineered for storage at room temperature with a verified 3-year shelf life. This eliminates the capital expenditure and logistical risks associated with cold chain monitoring and storage infrastructure failures.


B2B Quality & Risk Mitigation Matrix

Performance Metrics Authentic L&C BIO FILL® MegaFill (ADM) Generic / Low-Grade Dermal Alternatives
Immunogenicity Profile Ultra-low; complete cellular and antigen eradication via AlloClean® Variable; risk of residual cellular debris triggering inflammation
Structural Integrity & Volume Retention High stability; cross-linked network prevents premature resorption Low resistance to enzymatic degradation; high volume loss
Biocompatibility & Integration Promotes active fibroblast infiltration & microvascular long-growth Risk of fibrous encapsulation, thrombosis, or graft rejection
Storage & Logistics Requirements Room temperature stable; 3-year shelf life; zero cold-chain risk Requires strict temperature controls; prone to degradation
Donor-Site Complications Zero; completely replaces autologous tissue grafting High risk of donor-site pain, infection, and scarring

Strategic Clinical Applications & SEO Keywords

The L&C BIO FILL® MegaFill is clinically indicated for precision soft tissue augmentation and reconstructive procedures where hemodynamic stability and minimal tissue distortion are critical.

  • Rhinoplasty Defect Management: Ideal for nasal tip wrapping to provide structural cushioning and prevent silicone-induced skin thinning or extrusion.

  • Facial Contour Reconstruction: Restores symmetrical volume deficits caused by trauma, congenital anomalies, or tissue atrophy.

  • Depressed Scar & Wound Management: Promotes dermal tissue regeneration in deep, atrophic scars and covers chronic, non-healing cutaneous ulcers.

  • Post-Parotidectomy Barrier: Functions as a biological shield to prevent Frey’s syndrome and post-surgical tissue adhesion.


Strategic FAQ for Healthcare Procurement

Why is an intact extracellular matrix (ECM) critical for preventing graft failure and chronic inflammation?

An intact ECM retains the native collagen and elastin fibers required to signal host cell migration. If the matrix is damaged during purification, the host body recognizes it as a foreign object rather than a biological scaffold. This triggers foreign body giant cell reactions, leading to graft encapsulation, accelerated degradation, and ultimate clinical failure.

How does the MegaFill matrix minimize the risk of microvascular thrombosis post-implantation?

The AlloClean® process removes all cellular antigens and endothelial cell remnants that could induce platelet aggregation. By preserving a clean, biomimetic structural framework, the matrix allows smooth host microvascular長入 (vascularization) without inducing local endothelial stress or thrombosis.

What infrastructure savings does room-temperature storage offer to high-volume surgical centers?

Traditional allografts often require continuous deep-freeze monitoring systems. The lyophilized format of MegaFill eliminates the need for expensive medical refrigerators and backup power supplies, preventing asset loss caused by unexpected HVAC or cold-chain storage failures.


Technical Specifications

  • Product Identification: L&C BIO FILL® MegaFill

  • Manufacturer Part Number (MPN): Code 131100

  • Volumetric Quantity / Size: 350mg ( 片材 dimensions equivalent to 1cm × 5cm, Thickness: 0.7–0.9 mm)

  • Material Class: Human-derived Acellular Dermal Matrix (ADM)

  • Processing Methodology: Proprietary AlloClean® Purification & Cross-linking

  • Sterilization Method: Electron Beam (E-Beam) Irradiation

  • Packaging / Form: Lyophilized (Freeze-dried) Sheet, Single-Use Only

  • Regulatory Status: Accompanied by full import registration documentation for international distribution.

Listing Terms & Conditions

We ship worldwide, please inquire the shipping rate to your country before placing an order.

We carry all products of this brand in the listing, please let me know if you have any other inquires which is not listed in our store.

All purchases over $1,000 must be paid by wire transfer. We cannot accept international credit card payments for orders over $1,000.

Due to worldwide shipping delays, it is possible that items listed could be on backorder. If the item is unavailable for an extended period, we sincerely apologize for the delay. In this case, we will refund you as soon as we are notified of the backorder and contact you with the confirmation of refund.